Dopexamine hydrochloride

CAS No. 86484-91-5

Dopexamine hydrochloride( FPL60278AR )

Catalog No. M22574 CAS No. 86484-91-5

Dopexamine hydrochloride is a β2-adrenergic receptor agonist. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 160 In Stock
25MG 335 In Stock
50MG 500 In Stock
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Biological Information

  • Product Name
    Dopexamine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Dopexamine hydrochloride is a β2-adrenergic receptor agonist. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects.
  • Description
    Dopexamine hydrochloride is a β2-adrenergic receptor agonist. ?Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics, either blood pressure or stroke volume.Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors.?Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow.(In Vitro):Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors. Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics, either blood pressure or stroke volume.
  • In Vitro
    Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors. Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics, either blood pressure or stroke volume.
  • In Vivo
    ——
  • Synonyms
    FPL60278AR
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    β2-adrenergic receptor
  • Research Area
    Cancer
  • Indication
    Oral Cancer|Head and Neck Cancer;Free Flap;Hypotension

Chemical Information

  • CAS Number
    86484-91-5
  • Formula Weight
    429.42
  • Molecular Formula
    C22H34Cl2N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (232.87 mM)
  • SMILES
    Cl.Cl.Oc1ccc(CCNCCCCCCNCCc2ccccc2)cc1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bangash MN, et al. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow. Crit Care. 2013 Mar 28;17(2):R57.
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